Hi there,
Been using a Venue for several years now (and before that a Baggs PADI) ...it's an excellent unit, IMHO: dead quiet, completely transparent, and offers as little or as much tone shaping as you like.
As far as how much to tweak it, aside from the obvious personal tonal preferences, it also depends on which ES you have, the earlier versions "needing" more mid cut, and the current-generation ES needing very little tone shaping (I tend to cut at around 5-600Hz and around 1K, more or less). And I do
not use the pre-set notch filter with the ES, though it can be useful for other transducers that may have a propensity toward feedback BTW, I've tried it with both a balanced and unbalanced cable and find zero improvement in using a balanced line. A good-quality 1/4" cable straight into the input, and the XLR out to the snake yields superb results in my experience. Hope that helps you a bit
Edward